SS 38 - Radiation and Cancer Biology 4: Immunometabolism

Presentations

• 12:45pm - 12:55pm PT

  Lactate-Induced DNMT1 Lactylation in Dendritic Cells Epigenetically Silences STAT1 to Suppress Antigen Presentation and Drive Radioresistant Tumor Immune Evasion

  Speaker: Weitao Wen, PhD - Shandong Cancer Hospital Affiliated to Shandong First Medical University, Jinan
• 12:45pm - 02:00pm PT

  Radiation and Cancer Biology 4: Immunometabolism

  Speaker: Adam Mueller, MD, PhD - UPMC Cancer Center, Pittsburgh
• 12:45pm - 02:00pm PT

  Radiation and Cancer Biology 4: Immunometabolism

  Speaker: Aparna Kesarwala, MD, PhD - Emory University School of Medicine, Atlanta
• 12:55pm - 01:05pm PT

  Radiation Activates the AIM2 Inflammasome to Enhance Immunotherapy by Triggering IL-1ß Signaling and DC Activation in Colorectal Cancer

  Speaker: Fan Xia, MD, PhD - Fudan University Shanghai Cancer Center, Shanghai
• 01:05pm - 01:15pm PT

  Cholesterol Flux Rewiring through LDLR Palmitoylation Establishes a Mitochondrial Shield and Immune Desert in Radioresistant Tumors

  Speaker: Lingyi Kong, MD - Union Hospital Cancer Center, Tongji Medical College, HUST, Wuhan
• 01:15pm - 01:25pm PT

  Hypoxanthine Enforces Cytotoxic CD8⁺ T Cells via Purine Salvage Synthesis and Epigenetic Modification to Potentiate Immunotherapy

  Speaker: Lingyi Kong, MD - Union Hospital Cancer Center, Tongji Medical College, HUST, Wuhan
• 01:25pm - 01:35pm PT

  Low-Dose Radiotherapy Modulates Dendritic Cell Metabolism to Reprogram the Tumor Immune Microenvironment

  Speaker: Ningbo Liu, MD, PhD - Tianjin Medical University Cancer Institute and Hospital, Tianjin
• 01:35pm - 01:45pm PT

  Discussant

  Speaker: Stephen Shiao, MD, PhD - Cedars-Sinai Medical Center, Los Angeles