SS 15 - Radiation Biology 2: Novel Immunotherapeutics & Biomarker Discovery

Presentations

• 08:00am - 08:10am PT

  RC48-ADC Combined with Radiotherapy and Immunotherapy as Salvage Therapy for Advanced Solid Tumors with HER2 Expression: A Multicenter, Phase II Trial

  Speaker: Meiling Xu, MD, PhD, RT - The Second Affiliated Hospital of Soochow University, Suzhou
• 08:10am - 08:20am PT

  Single-Cell RNA Sequencing to Reveal Cellular Mechanisms Driving Differential Responses to Radiotherapy Combined with Systemic Therapy and Immunotherapy in MSS Locally Advanced Rectal Cancer with vs. without Liver Metastases

  Speaker: Yaqi Wang, MD - Fudan University Shanghai Cancer Center, Shanghai
• 08:20am - 08:30am PT

  Single-Cell Profiling Reveals Dynamics TIME Remodeling after Neoadjuvant Radiotherapy Followed by Chemotherapy and Immune Checkpoint Blockade in pMMR/MSS LARC

  Speaker: Yinan Chen, PhD - Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing
• 08:30am - 08:40am PT

  Preclinical Evaluation of First-in-Class PROTAC Survivin Degrader HMAK101 for Radiosensitization for GBM, DIPG and Brain Metastases

  Speaker: Shuhua Zheng, DO, PhD - Northwestern Feinberg School of Medicine, Chicago
• 08:40am - 08:50am PT

  A Novel Therapeutic Approach Using ENO1-specific CAR-NK Cells to Target KRAS-Mutated Cancers

  Speaker: K.S. Clifford Chao, MD - China Medical University, Taiwan, Taichung
• 08:50am - 09:00am PT

  Discussant

  Speaker: Kristina Young, MD, PhD - Earle A. Chiles Research Institute, Portland